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    Go to the top of the page   ID: 20041222171655 Original case in english  More links about this topic on Pubmed (PubMed Reader)
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    Hepatoblastoma
    G Hahn. Hepatoblastoma. PedRad [serial online] vol 4, no. 12.
    URL: www.PedRad.info/?search=20041222171655


     
     Pediatric Radiology CasesImages to this case: There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     Pediatric Radiology CasesAuthor/s:

    G. Hahn (Bereich Kinderradiologie/Uniklinikum Dresden/Deutschland)  

     
     Pediatric Radiology CasesEmail Address:

    Viewable for logged on visitors (Log on)  

     
     Pediatric Radiology CasesAge:

    6 Months  

     
     Pediatric Radiology CasesGender:

    Female  

     
     Pediatric Radiology CasesRegion-Organ:

    Abdomen-Liver  

     
     Pediatric Radiology CasesMost likely etiology:

    neoplastic  

     
     Pediatric Radiology CasesHistory:

    In a routine sonographical examination in a child with previously known Beckwith-Wiedemann Syndrome, a large tumor of the liver was found. Proof of slight scleral jaundice. Markedly increased alpha-fetoprotein in the blood.  

     
     Pediatric Radiology CasesPathomorphology or Pathophysiology of this disease :

    Hepatoblastomas is a malignant embryonal mixed tumor, which derives from epithelial and/or mesechymal cellular elements. It occurs in early childhood.
    In Beckwith-Wiedemann Syndrome, one findes more commonly nephroblastomas and hepatoblastomas.
    In increased alpha-fetoprotein in the blood and proof of a typical hepatic tumor in MRI, the diagnosis is relatively easy and there is no histological proof needed before starting chemotherapy.  

     
     Pediatric Radiology CasesRadiological findings:


    MRI 1 <- view MRI 1

    MRI 1: T2 transverse: Inhomogenic, partly focally hyperintense and partly hypointense, mass of ca. 9 x 7 x 12 cm in size in the right and left hepatic lobe. The vena portae is considerably compressed ventrally and is pushed to the left, as is the pancreas. The gall bladder is no longer demarcated.
    The right kidney is compressed from above and thus has moved caudally. The vena cava's lumen is reduced to a slit due to compression in the region of the tumor.




    MRI 2 <- view MRI 2

    MRI 2: T2 coronal: Inhomogenic, partly focally hyperintense and partly hypointense, mass of ca. 9 x 7 x 12 cm in size in the right and left hepatic lobe.




    MRI 3 <- view MRI 3

    MRI 3: T1 transversal: Inhomogenic, partly focally hyperintense and partly hypointense, mass of ca. 9 x 7 x 12 cm in size in the right and left hepatic lobe.The right kidney is compressed from above and thus has moved caudally.




    MRI 4 <- view MRI 4

    MRI 4: T1 sagittal, contrast media, fat saturation: After contrast media application, inhomogenic enhancement of the intrahepatic mass, which in the T1-sequence allows delimination of focally hyperintense masses of only a few millimeters.




    MRI 5 <- view MRI 5

    MRI 5: T1 coronar, contrast media, fat saturation: After contrast media application, inhomogenic enhancement of the intrahepatic mass, which in the T1-sequence allows delimination of focally hyperintense masses of only a few millimeters.




    MRI 6 <- view MRI 6

    MRI 6: T1 transversal, contrast media, fat saturation: After contrast media application, inhomogenic enhancement of the intrahepatic mass, which in the T1-sequence allows delimination of focally hyperintense masses of only a few millimeters.



     

     
     Pediatric Radiology CasesDiagnosis confirmation:

    Surgery / Histo  

     
     Pediatric Radiology CasesWhich DD would be also possible with the radiological findings:

    Hepatocellular carcinoma, in childhood rare.  

     
     Pediatric Radiology CasesCourse / Prognosis / Frequency / Other :

    In good size reduction through chemotherapy and following complete surgical resection, the prognosis is very good.  

     
     Pediatric Radiology CasesComments of the author about the case:

    N/A  

     
     Pediatric Radiology CasesFirst description / History:

    N/A  

     
     Pediatric Radiology CasesLiterature:

    N/A  

     
     Pediatric Radiology CasesKeywords:

    Beckwith-Wiedemann Syndrome, Hepatoblastoma, malignant embryonal mixed tumor, child, childhood, pediatric radiology  

     
     Pediatric Radiology Cases Cite this article:

    G Hahn. Hepatoblastoma. PedRad [serial online] vol 4, no. 12.
    URL: www.PedRad.info/?search=20041222171655  

     
     Pediatric Radiology Cases Read similar articles: with corresponding keywords
    in the same field: Abdomen-Liver
    or in the region: Abdomen
    or in the tissue/organ: Liver
    or with the etiology: neoplastic
     
     Pediatric Radiology CasesImages to this case: There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     
    Hepatoblastoma
    G Hahn. Hepatoblastoma. PedRad [serial online] vol 4, no. 12.
    URL: www.PedRad.info/?search=20041222171655


     

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    Hepatoblastoma
    Other cases by these authors:

    Search G. Hahn in Medline G. Hahn (22)   

    Hepatoblastoma  
     
    Hepatoblastoma
    G Hahn. Hepatoblastoma. PedRad [serial online] vol 4, no. 12.
    URL: www.PedRad.info/?search=20041222171655


     

    Which diagnosis have other collegues guessed?


    • Liver cirrhosis
      Votes: 0 (0 %)


    • Hepatocellular carcinoma
      Votes: 0 (0 %)


    • Hepatoblastoma
      Votes: 13 (92 %)


    • Follicular nodular hyperplasia
      Votes: 1 (7 %)


    • Hemangioma
      Votes: 0 (0 %)



        Total answers: 14

     
    Hepatoblastoma
    G Hahn. Hepatoblastoma. PedRad [serial online] vol 4, no. 12.
    URL: www.PedRad.info/?search=20041222171655


     

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    Hepatoblastoma
    G Hahn. Hepatoblastoma. PedRad [serial online] vol 4, no. 12.
    URL: www.PedRad.info/?search=20041222171655


     




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