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    Go to the top of the page   ID: 20020815184849 Original case in english  More links about this topic on Pubmed (PubMed Reader)
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    Pilocytic astrocytoma
    H Frimmel. Pilocytic astrocytoma. PedRad [serial online] vol 2, no. 8.
    URL: www.PedRad.info/?search=20020815184849


    ( There are questions in the CMK-Mode for this topic )

     
     Pediatric Radiology CasesImages to this case: There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     Pediatric Radiology CasesAuthor/s:

    H. Frimmel (Halle/S.)  

     
     Pediatric Radiology CasesEmail Address:

    Viewable for logged on visitors (Log on)  

     
     Pediatric Radiology CasesAge:

    5 Years  

     
     Pediatric Radiology CasesGender:

    Female  

     
     Pediatric Radiology CasesRegion-Organ:

    Head-Brain and brain nerves  

     
     Pediatric Radiology CasesMost likely etiology:

    neoplastic  

     
     Pediatric Radiology CasesHistory:

    5.5 year-old girl with increased vision loss, opticus atrophy on both sides.  

     
     Pediatric Radiology CasesPathomorphology or Pathophysiology of this disease :

    Low malignant astrocytoma. WHO-Grade I, usually in children and adolescents.
    It is a brain tumor of the astroglia with solid and cystic parts. Calcifications are rare.
    Most often located in: Chiasma opticum, Hypothalamus/3rd ventricle, brain stem, cerebellum/4th ventricle.  

     
     Pediatric Radiology CasesRadiological findings:


    MRI 1 <- view MRI 1

    MRI 1: T2 FLAIR transversal: multilobed tumor located in the suprasellar region. High in signals.







    MRI 2 <- view MRI 2

    MRI 2: T2 TIRM transversal: 4.5 x 3 x 3 cm large, solid part (hyperintense), two cystic areas measuring 2 x 1.5 x 1.5 cm ventrally and 4 x 3 x 2.5 cm dorsally of the solid part.







    MRI 3 <- view MRI 3

    MRI 3: T1 transversal - no contrast: multilobed tumor located in the suprasellar region. Inhomogenically hypointense







    MRI 4 <- view MRI 4

    MRI 4: T1 transversal after contrast application: 4.5 x 3 x 3 cm solid content (with enhancement), both cystic areas (2 x 1.5 x 1.5 cm ventrally and 4 x 3 x 2.5 cm dorsally to the solid part) with contrast uptake along the edges.






    MRI 5 <- view MRI 5

    MRI 5: T1 coronar after contrast application: 4.5 x 3 x 3 cm solid content (with enhancement), both cystic areas (2 x 1.5 x 1.5 cm ventrally and 4 x 3 x 2.5 cm dorsally to the solid part) with contrast uptake along the edges.







    MRI 6 <- view MRI 6

    MRI 6: T1 sagittal after contrast application: 4.5 x 3 x 3 cm solid content (with enhancement), both cystic areas (2 x 1.5 x 1.5 cm ventrally and 4 x 3 x 2.5 cm dorsally to the solid part) with contrast uptake along the edges.



     

     
     Pediatric Radiology CasesDiagnosis confirmation:

    Surgery / Histo  

     
     Pediatric Radiology CasesWhich DD would be also possible with the radiological findings:

    Craniopharyngeoma - up to 50-57% (other literature 80-90%) calcifications. Typical hypointensity of the cystic parts in the T1-weighted images, as well as iso- or hyperintensity of the solid parts (hypointense with calcifications), in T2-weighted images, inhomogenic hyperintensity of the tumor. After contrast media, strong enhancement of the vital tumor, often variable morphology and signal pattern (depending on the cyst's contents, extent of the calcifications, relation of solid/cystic tumor parts).  

     
     Pediatric Radiology CasesCourse / Prognosis / Frequency / Other :

    Low-malignancy, slow-growing glioma WHO-grade I.

    Seldom malignant transformation in WHO Grade II.
    Pilocytic astromcytomas are cause of about 5-10% of all giomas and about 30% of all brain tumors in children. Most children are the age of 10. Often, a radical surgery is not possible. Radiation treatment after histologic diagnosis confirmation.  

     
     Pediatric Radiology CasesComments of the author about the case:

    The often variable picture of the different cerebral tumors regarding the morphology and signal behavior doesn't alone allow a histologic grading because of imaging. In cystic tumor parts, one should always consider a pilocytic astrocytoma.  

     
     Pediatric Radiology CasesFirst description / History:

    N/A  

     
     Pediatric Radiology CasesLiterature:

    1. Medline: Medline
    K.Sartor
    "Neuroradiologie"
    2.Auflage
    Georg-Thieme-Verlag 2001

    2. Medline: Medline
    D.Uhlenbrock
    "MRT und MRA des Kopfes"
    Georg-Thieme-Verlag 1996  

     
     Pediatric Radiology CasesKeywords:

    pilocytic, astrocytoma, brain tumor, pilocytic astrocytoma, low malignant astrocytoma, child, childhood, pediatric radiology  

     
     Pediatric Radiology Cases Cite this article:

    H Frimmel. Pilocytic astrocytoma. PedRad [serial online] vol 2, no. 8.
    URL: www.PedRad.info/?search=20020815184849  

     
     Pediatric Radiology Cases Read similar articles: with corresponding keywords
    in the same field: Head-Brain and brain nerves
    or in the region: Head
    or in the tissue/organ: Brain and brain nerves
    or with the etiology: neoplastic
     
     Pediatric Radiology CasesImages to this case: There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     
    Pilocytic astrocytoma
    H Frimmel. Pilocytic astrocytoma. PedRad [serial online] vol 2, no. 8.
    URL: www.PedRad.info/?search=20020815184849


    ( There are questions in the CMK-Mode for this topic )

     

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    Pilocytic astrocytoma
    Other cases by these authors:

    Search H. Frimmel in Medline H. Frimmel (7)   

    Pilocytic astrocytoma  
     
    Pilocytic astrocytoma
    H Frimmel. Pilocytic astrocytoma. PedRad [serial online] vol 2, no. 8.
    URL: www.PedRad.info/?search=20020815184849


    ( There are questions in the CMK-Mode for this topic )

     
     
    Pilocytic astrocytoma
    H Frimmel. Pilocytic astrocytoma. PedRad [serial online] vol 2, no. 8.
    URL: www.PedRad.info/?search=20020815184849


    ( There are questions in the CMK-Mode for this topic )

     

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    Pilocytic astrocytoma
    H Frimmel. Pilocytic astrocytoma. PedRad [serial online] vol 2, no. 8.
    URL: www.PedRad.info/?search=20020815184849


    ( There are questions in the CMK-Mode for this topic )

     




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