A. Schlüter (Halle)  

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Head-Brain and brain nerves  

neoplastic  

The MRI was done because of seizures. Proof of various cutaneous giant cell naevi in the region of the dorsum.  

Localized leptomeningeal naevus infestation of intracranial or intraspinal structures. Neurologically symptomatic and asymptomatic forms are differentiated. Serious neurological symptoms can be seen depending on the localization (i.e. CSF circulatory disfunction, compression of the spinal cord).  

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MRI 1: Transversal (T1 - native)






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MRI 2: Transversal (T1 - native)

Depending on the melanin content of the lesions, the lesions can be seen even in the T1 weighted image as hyperintensive lesions. After contrast application, one may see enchancement (subtraction images are recommended). In the T2 weighted series, there are different characteristics of the tumors, depending on the extent of the regressive changes.




 

Total constellation (Consens)  

Melanoma metastases. Hemorrhaging metastases, or rather tumors of other origin.  

The extent of the clinical symptoms and prognosis is dependent on the localization in the CNS. A malignant change is pricipally possible.  

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1. Medline:
Foster RD, Williams ML, Barkovich AJ, Hoffman WY, Mathes SJ, Frieden IJ
Giant congenital melanocytic nevi: the significance of neurocutaneous melanosis in neurologically asymptomatic children
Plast Reconstr Surg. 2001 Apr 1;107(4):933-41

2. Medline:
Helmbold P, Rompel R, Petres J, Lubbe D, Marsch WC
Congenital melanocytic nevi
Hautarzt. 1999 Nov;50(11):779-84  

Neurocutaneous, melanosis, childhood, neurocutaneous melanosis, seizures, cutaneous giant cell naevi, child, childhood, pediatric radiology  

A Schlüter. Neurocutaneous melanosis of the childhood. PedRad [serial online] vol 1, no. 11.
URL: www.PedRad.info/?search=20011126144208