Ina Sorge, Wolfgang Hirsch, W. Köpernik (Leipzig / Halle)  

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14 Years  

Female  

Thorax-Lung  

inflammatory or infectious  

14 year-old girl with ALL, after the 2nd round of chemotherapy sudden onset of fever, fatigue, cough.  

Aspergillus is ubiquitous.

Included with "Aspergillosis," are the following illnesses:
-allergic pulmonary illness due to aspergillus
-mucomembraneous, broncial Aspergillosis
-aspergillus pneumonia
-invasive aspergillosis

The last form of aspergillosis is seen only in immunosupressed patients.  

<- view X-Ray 1

X-Ray 1: X-ray p.a.: Representation of many alveolar, confluent opaque figures in both upper, both middle and left lower lobes.



<- view MRI 1

MRI 1: T2-weighted TSE-sequence coronal (breath triggered). The alveolar infiltration is proven by high-resolution, hyperintense infiltrations of the alveolar space.



<- view MRI 2

MRI 2: T1-weighted Gradient-echo sequence coronal without contrast media (VIBE-Sequence).



<- view MRI 3

MRI 3: Synopsis of the x-ray findings and the MRI findings. (various weights)

 

Laboratory diagnostics  

invasive aspergillosis, pneumonia, atelectasis  

Prognosis of invasive aspergillosis in an advanced case is often bad, even with treatment with amphoterecin-B (because of the corresponding immunosupression).  

N/A  

N/A  

1. Medline:
Vaideeswar P, Prasad S, Deshpande JR, Pandit SP.
Invasive pulmonary aspergillosis: A study of 39 cases at autopsy.
J Postgrad Med. 2004 Jan-Mar;50(1):21-6.

2. Medline:
Franquet T, Muller NL, Oikonomou A, Flint JD.
Aspergillus infection of the airways: computed tomography and pathologic findings.
J Comput Assist Tomogr. 2004 Jan-Feb;28(1):10-6.
 

Aspergillosis, immunosuppresion, invasive Aspergillosis, ALL, Acute Lymphatic Leucemia, chemotherapy, child, childhood, pediatric radiology  

Ina Sorge, Wolfgang Hirsch, W Köpernik. Invasive Aspergillosis. PedRad [serial online] vol 4, no. 5.
URL: www.PedRad.info/?search=20040501114127