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    Go to the top of the page   ID: 20011103135037 ( 268 times read ) Original case in english  More links about this topic on Pubmed (PubMed Reader)
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    This case was evaluated as very interesting (Grade 7.8).

     
    Microadenomas of the pituitary gland
    Wolfgang Hirsch, A Jassoy. Microadenomas of the pituitary gland. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011103135037


    ( There are questions in the CMK-Mode for this topic )

     
     Pediatric Radiology CasesImages to this case: There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     Pediatric Radiology CasesAuthor/s:

    Wolfgang Hirsch, A. Jassoy (Halle)  

     
     Pediatric Radiology CasesEmail Address:

    Viewable for logged on visitors (Log on)  

     
     Pediatric Radiology CasesAge:

    N/A  

     
     Pediatric Radiology CasesGender:

    N/A  

     
     Pediatric Radiology CasesRegion-Organ:

    Head-Other or unknown  

     
     Pediatric Radiology CasesMost likely etiology:

    neoplastic  

     
     Pediatric Radiology CasesHistory:

    Symptoms, which are mostly seen as an overactivity of the anterior pituitary. (I.e. large size, breast secretions, hypergonadism, hyperthyroidism, and others).  

     
     Pediatric Radiology CasesPathomorphology or Pathophysiology of this disease :

    Adenomas are more frequently found in healthy children and adolescents without any hormone defects (= incidentalomas).

    Localized adenomas are rarer in hyperprolactemia; in IGF/BP3 it is higher.

    According to definition, macroadenomas are larger than 10 mm.  

     
     Pediatric Radiology CasesRadiological findings:


    MRI 1 <- view MRI 1

    MRI 1: T1 native - Coronal
    Mostly hypointense or not well-marcated (isointense)





    MRI 2 <- view MRI 2

    MRI 2: T1 with contrast - Coronal
    After contrast application in the early phase, there is a good hypointense demarcation of the microadenoma, therefore dynamic contrast sequences are of value.





    MRI 3 <- view MRI 3

    MRI 3: T1 with contrast- Sagittal
    Posterior pituitary is hyperintense (Signal intensity is dependent on the functionality of the posterior pituitary), the anterior pituitary shows some signal intensity.





    MRI 4 <- view MRI 4

    MRI 4: T2 - Coronal
    Rarely hypertense in T2 weighted images. Most often T2-weighted images show no advantage.

    One-sided lowering of the sella floor, or lifting of the sella upper wall, asymmetry and/or elongation of the pituitary stalk.



     

     
     Pediatric Radiology CasesDiagnosis confirmation:

    Total constellation (Consens)  

     
     Pediatric Radiology CasesWhich DD would be also possible with the radiological findings:

    Tumor, Hemorrhage, Cyst  

     
     Pediatric Radiology CasesCourse / Prognosis / Frequency / Other :

    N/A  

     
     Pediatric Radiology CasesComments of the author about the case:

    In autopsy reports/statistics, there are 3-27% incidentalomas reported. Probably they are diagnosed as microadenomas in MRI.  

     
     Pediatric Radiology CasesFirst description / History:

    N/A  

     
     Pediatric Radiology CasesLiterature:

    1. Medline: Medline
    W.Hirsch et al
    Microadenomas of the pituitary gland in children with and without hypophyseal dysfunction in magnetic resonance imaging
    JPEM (15) 2002 , 157-162  

     
     Pediatric Radiology CasesKeywords:

    Microadenoma, Macroadenoma, pituitary gland, microadenomas of the pituitary gland, increased body height, breast secretions, hypergonadism, hyperthyroidism, hormone secreting, adenoma, child, childhood, pediatric radiology  

     
     Pediatric Radiology Cases Cite this article:

    Wolfgang Hirsch, A Jassoy. Microadenomas of the pituitary gland. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011103135037  

     
     Pediatric Radiology Cases Read similar articles: with corresponding keywords
    in the same field: Head-Other or unknown
    or in the region: Head
    or in the tissue/organ: Other or unknown
    or with the etiology: neoplastic
     
     Pediatric Radiology CasesImages to this case: There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     
    Microadenomas of the pituitary gland
    Wolfgang Hirsch, A Jassoy. Microadenomas of the pituitary gland. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011103135037


    ( There are questions in the CMK-Mode for this topic )

     

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    Microadenomas of the pituitary gland
    Other cases by these authors:

    Search Wolfgang Hirsch in Medline Wolfgang Hirsch (17)   
    Search A. Jassoy in Medline A. Jassoy (6)   

    Microadenomas of the pituitary gland  
     
    Microadenomas of the pituitary gland
    Wolfgang Hirsch, A Jassoy. Microadenomas of the pituitary gland. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011103135037


    ( There are questions in the CMK-Mode for this topic )

     
     
    Microadenomas of the pituitary gland
    Wolfgang Hirsch, A Jassoy. Microadenomas of the pituitary gland. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011103135037


    ( There are questions in the CMK-Mode for this topic )

     

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    How interesting was this case for you?
    (10 = most interesting || 1 = less interesting)
    This case was evaluated as very interesting (Grade 7.8).

     
    Microadenomas of the pituitary gland
    Wolfgang Hirsch, A Jassoy. Microadenomas of the pituitary gland. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011103135037


    ( There are questions in the CMK-Mode for this topic )

     




    Discussion >> Write Comment <<


    Mikroadenome der Hypophyse:  mikroadenom
    (nina | 12.02.10)


    hallo mein nme ist nina ich bin 21 jahre und bei mir wurde vor 3 wochen ein mikroadenom endeckt ich hab ständig starke kopfschmerzen und meine tage blieb 5 monate aus und manchmal ist es nicht mehr auszuhalten ich nehme zurzeit medikamente wegen mein Prolaktinspiegel weil es ziehmlich hoch ist ja in 6 wochen muss ich wieder zum arzt um mein blut zu untersuchen
    kann mir jemand erklähren was das überhaupt bedeutet kann mann es auch operieren wenn es klein ist warscheinlich hört bei mir die schmerzen im kopf dan auf



      re: Mikroadenome der Hypophyse:  mikroadenom
      (Roland Talanow | 12.02.10)


      Prolaktin-sezernierende Tumoren haben eine Rezidiv-Rate von ungefaehr 50%. Deshalb ist die medikamentoese Therapie erst einmal bevorzugt. Falls zur Operation entschlossen wurde, ist der trans-sphenoidale Eingriff am effektivsten. Postoperative Radiotherapie scheint nicht effektiv zu sein. Einige Zentren fuehren "Gamma-Knife" Bestrahlung fuer wiederkehrende Tumoren durch.
      Ich hoffe dies hat geholfen.








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