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    Go to the top of the page   ID: 20090528153613 Original case in english  More links about this topic on Pubmed (PubMed Reader)
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    Oligodendroglioma:presenting as supratentorial cerebral mass in a child
    Sanjeeb Kumar. Oligodendroglioma:presenting as supratentorial cerebral mass in a child. PedRad [serial online] vol 9, no. 5.
    URL: www.PedRad.info/?search=20090528153613


     
     Pediatric Radiology CasesImages to this case: There are CT-images available for this case. [ CT ] View all modalities [ All ]   
     Pediatric Radiology CasesAuthor/s:

    Sanjeeb Kumar Sarma ( Down Town Hospital/ Guwahati/ India)  

     
     Pediatric Radiology CasesEmail Address:

    Viewable for logged on visitors (Log on)  

     
     Pediatric Radiology CasesAge:

    6 Years  

     
     Pediatric Radiology CasesGender:

    Female  

     
     Pediatric Radiology CasesRegion-Organ:

    Head-Brain and brain nerves  

     
     Pediatric Radiology CasesMost likely etiology:

    neoplastic  

     
     Pediatric Radiology CasesHistory:

    Six year old female child presenting with on and off headache since last 6 to 7 months. Parents also observed a few episodes of seizures in last two months.  

     
     Pediatric Radiology CasesPathomorphology or Pathophysiology of this disease :

    Oligodendrogliomas are uncommon gliomas. They arise from a specific type of glial cells, the oligodendrocytes, that make and maintain the CNS myelin. They are typically white matter tumors that may extend into the cortex and leptomeninges. Oligodendrogliomas comprise 2 - 5% of all primary brain tumors and 5 - 10% of gliomas. Adults are more affected than children (8:1), peak age being 35-45 years. Although they can be found anywhere, the most common site being the frontal lobes.
    On plain X-ray of skull calcifications may be seen if the tumor is densely calcified. Angiographycally this tumor is avascular or faintly vascular that shows focal stretching and draping of cortical vessels around the lesion in low grade type, whereas the malignant ones may have significant vascularity. Oligodendrogliomas are the most common intracranial tumors to calcify. Non-contrast CT scans show a partially calcified (70-90% of all cases show calcification) mixed density hemispheric mass that extends peripherally to the cortex. Scalloped erosion of the inner table is seen in some larger masses. Cystic degeneration is common but frank intra-tumoral hemorrhage and edema is distinctly uncommon. Mild to moderate enhancement after intravenous contrast is seen in two third of cases. MR scans show mixed hypo- and isointense areas on T1W1 and hyperintense foci on T2 weighted sequences. Enhancement is typically patchy and moderate.
    Treatment is surgical removal of the mass.
     

     
     Pediatric Radiology CasesRadiological findings:


    CT 1 <- view CT 1

    CT 1: CT scannogram showing tumoral calcifications (white arrow) and pressure effect over inner calvarial table (black arrow) of right parietal bone.




    CT 2 <- view CT 2

    CT 2: Axial non-contrast CT section showing iso to slightly hyperdense mass with both solid (white arrow) and cystic (black arrow) components. The tumor measures 65x55x40 mm in its widest diameters.





    CT 3 <- view CT 3

    CT 3: Axial non-contrast CT section showing multiple cystic components within the tumor (black arrows).No intra tumoral hemorrhage seen





    CT 4 <- view CT 4

    CT 4: Axial non-contrast CT section showing tumoral calcifications ( black arrow).





    CT 5 <- view CT 5

    CT 5: Axial contrast CT section showing mild to moderate non-homogenous enhancement of solid component of the tumor.





    CT 6 <- view CT 6

    CT 6: Axial contrast CT section showing the same mass at a higher level in the right parietal lobe.





    CT 7 <- view CT 7

    CT 7: Axial CT section in bone window showing clearly the erosion (black arrow) of inner table of right parietal bone and tumoral calcifications (white arrow).




     

     
     Pediatric Radiology CasesDiagnosis confirmation:

    Surgery / Histo  

     
     Pediatric Radiology CasesWhich DD would be also possible with the radiological findings:

    Astrocytoma  

     
     Pediatric Radiology CasesCourse / Prognosis / Frequency / Other :

    Most oligodendrogliomas are slow growing neoplasms; only a minority cases are anaplastic. Tumor grade is the single most important prognostic factor. Patients with low grade lesions have 5 and 10 year survival rates of 74% and 46% respectively, whereas these rates reduced to 41% and 20% for grade 3 and grade 4 tumors.  

     
     Pediatric Radiology CasesComments of the author about the case:

    Though oligodendroglioma is not uncommon in adults, however it is distinctly rare in pediatric age group. This is a biopsy proven case and is of low grade type. Patient was clinically well postoperatively and was advised to come for follow up.  

     
     Pediatric Radiology CasesFirst description / History:

    N/A  

     
     Pediatric Radiology CasesLiterature:

    Diagnostic Neuroradiology by Anne G. Osborn (Mosby)- chapter 13- Astrocytomas and other glial neoplasms P- 563-566.  

     
     Pediatric Radiology CasesKeywords:

    Oligodendroglioma, glioma, supratentorial mass, calcified cerebral mass, child, childhood, pediatric radiology  

     
     Pediatric Radiology Cases Cite this article:

    Sanjeeb Kumar. Oligodendroglioma:presenting as supratentorial cerebral mass in a child. PedRad [serial online] vol 9, no. 5.
    URL: www.PedRad.info/?search=20090528153613  

     
     Pediatric Radiology Cases Read similar articles: with corresponding keywords
    in the same field: Head-Brain and brain nerves
    or in the region: Head
    or in the tissue/organ: Brain and brain nerves
    or with the etiology: neoplastic
     
     Pediatric Radiology CasesImages to this case: There are CT-images available for this case. [ CT ] View all modalities [ All ]   
     
    Oligodendroglioma:presenting as supratentorial cerebral mass in a child
    Sanjeeb Kumar. Oligodendroglioma:presenting as supratentorial cerebral mass in a child. PedRad [serial online] vol 9, no. 5.
    URL: www.PedRad.info/?search=20090528153613


     

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    Oligodendroglioma:presenting as supratentorial cerebral mass in a child
    Other cases by these authors:

    Search Sanjeeb Kumar Sarma in Medline Sanjeeb Kumar Sarma (8)   

    Oligodendroglioma:presenting as supratentorial cerebral mass in a child  
     
    Oligodendroglioma:presenting as supratentorial cerebral mass in a child
    Sanjeeb Kumar. Oligodendroglioma:presenting as supratentorial cerebral mass in a child. PedRad [serial online] vol 9, no. 5.
    URL: www.PedRad.info/?search=20090528153613


     
     
    Oligodendroglioma:presenting as supratentorial cerebral mass in a child
    Sanjeeb Kumar. Oligodendroglioma:presenting as supratentorial cerebral mass in a child. PedRad [serial online] vol 9, no. 5.
    URL: www.PedRad.info/?search=20090528153613


     

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    Oligodendroglioma:presenting as supratentorial cerebral mass in a child
    Sanjeeb Kumar. Oligodendroglioma:presenting as supratentorial cerebral mass in a child. PedRad [serial online] vol 9, no. 5.
    URL: www.PedRad.info/?search=20090528153613


     




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