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    Go to the top of the page   ID: 20070724201543 Original case in english  More links about this topic on Pubmed (PubMed Reader)
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    Ectopic Thymus
    Veronika Huf, Kurt Vollert, Tobias Schuster. Ectopic Thymus. PedRad [serial online] vol 7, no. 7.
    URL: www.PedRad.info/?search=20070724201543


     
     Pediatric Radiology CasesImages to this case: There are Ultrasound-images available for this case. [ Ultrasound ] There are MRI-images available for this case. [ MRI ] There are OP-Situs-images available for this case. [ OP-Situs ] There are Histology-images available for this case. [ Histology ] View all modalities [ All ]   
     Pediatric Radiology CasesAuthor/s:

    Veronika Huf (Klinikum Augsburg/Abteilung Kinderradiologie/Augsburg/Deutschland), Kurt Vollert (Klinikum Augsburg/Abteilung Kinderradiologie/Augsburg/Deutschland), Tobias Schuster (Klinikum Augsburg/Abteilung Kinderchirurgie/Augsburg/Deutschland)  

     
     Pediatric Radiology CasesEmail Address:

    Viewable for logged on visitors (Log on)  

     
     Pediatric Radiology CasesAge:

    6 Months  

     
     Pediatric Radiology CasesGender:

    Male  

     
     Pediatric Radiology CasesRegion-Organ:

    Neck-Other and unknown  

     
     Pediatric Radiology CasesMost likely etiology:

    congenital  

     
     Pediatric Radiology CasesHistory:

    Swelling in the right mandibular angle, movable, indolent,stable size for over 2 months.  

     
     Pediatric Radiology CasesPathomorphology or Pathophysiology of this disease :

    Normal development: Cells of the ventral bud of the 3rd pharyngeal pouch detach and migrate in the 8th gestational week caudally and medially towards the thyroid. They migrate further retrosternally into the superior mediastinum.

    Development of ectopic thymus tissue:
    1. Cells detach along the descensus path and proliferate -> development of accessory thymus tissue.
    2. The entire gland or a lobe does not descend and stays at loco -> ectopic thymus tissue.  

     
     Pediatric Radiology CasesRadiological findings:


    Ultrasound 1 <- view Ultrasound 1

    Ultrasound 1: Ultrasound of the tumor in the right mandibular angle which is hypoechoic and extending deeply into the soft tissue.




    Ultrasound 2 <- view Ultrasound 2

    Ultrasound 2: The tumor extends between the neck vessels (internal jugular vein and common carotid artery) without signs of invasion.



    Ultrasound 3 <- view Ultrasound 3

    Ultrasound 3: Good vascularization on Doppler ultrasound



    MRI 1 <- view MRI 1

    MRI 1: T1w noncontrast axial; the tumor is nearly isointense to muscle. The hyperintense areas represent predominantly protein-rich cysts or fat.





    MRI 2 <- view MRI 2

    MRI 2: T2w SPIR axial; The known tumor is hyperintense to muscle.





    OP-Situs 1 <- view OP-Situs 1

    OP-Situs 1: intraoperative findings of the tumor in the right mandibular angle




    Histology 1 <- view Histology 1

    Histology 1: Hassall's bodies in the central portions of the specimen.




    Histology 2 <- view Histology 2

    Histology 2: Hassall's bodies in the central portions of the specimen.



     

     
     Pediatric Radiology CasesDiagnosis confirmation:

    Surgery / Histo  

     
     Pediatric Radiology CasesWhich DD would be also possible with the radiological findings:

    Hemangioma, Metastasis, Teratoma, Sarcoma, Thyroid tumor  

     
     Pediatric Radiology CasesCourse / Prognosis / Frequency / Other :

    Ectopic thymus tissue is more frequently prevalent than traditionally suggested. With improved diagnostic modalities (e.g. ultrasound) the diagnosis is more frequently made. 61 % of 18 children who were examined in the neck area had ectopic thymus tissue in the neck according to the literature (see reference). Since we were sensitized for this diagnosis, we diagnosed at least 4 children with ectopic thymus tissue as an incidental finding.
    Rarely, a malignant transformation of ectopic thymus tissue has been described in the literature. Thus, in our opinion is a conservative/awaiting position with follow up imaging studies justified.  

     
     Pediatric Radiology CasesComments of the author about the case:

    N/A  

     
     Pediatric Radiology CasesFirst description / History:

    N/A  

     
     Pediatric Radiology CasesLiterature:

    1. Medline: Medline
    Chu WXW, Metreweli C
    Ectopic thymic tissue in the paediatric age group
    Acta Radiologica 2002;43:144-6  

     
     Pediatric Radiology CasesKeywords:

    ectopic thymus,neck swelling,accessory thymus, child, childhood, pediatric radiology  

     
     Pediatric Radiology Cases Cite this article:

    Veronika Huf, Kurt Vollert, Tobias Schuster. Ectopic Thymus. PedRad [serial online] vol 7, no. 7.
    URL: www.PedRad.info/?search=20070724201543  

     
     Pediatric Radiology Cases Read similar articles: with corresponding keywords
    in the same field: Neck-Other and unknown
    or in the region: Neck
    or in the tissue/organ: Other and unknown
    or with the etiology: congenital
     
     Pediatric Radiology CasesImages to this case: There are Ultrasound-images available for this case. [ Ultrasound ] There are MRI-images available for this case. [ MRI ] There are OP-Situs-images available for this case. [ OP-Situs ] There are Histology-images available for this case. [ Histology ] View all modalities [ All ]   
     
    Ectopic Thymus
    Veronika Huf, Kurt Vollert, Tobias Schuster. Ectopic Thymus. PedRad [serial online] vol 7, no. 7.
    URL: www.PedRad.info/?search=20070724201543


     

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    Ectopic Thymus
    Other cases by these authors:

    Search Veronika Huf in Medline Veronika Huf (1)   
    Search Kurt Vollert in Medline Kurt Vollert (2)   
    Search Tobias Schuster in Medline Tobias Schuster (1)   

    Ectopic Thymus  
     
    Ectopic Thymus
    Veronika Huf, Kurt Vollert, Tobias Schuster. Ectopic Thymus. PedRad [serial online] vol 7, no. 7.
    URL: www.PedRad.info/?search=20070724201543


     
     
    Ectopic Thymus
    Veronika Huf, Kurt Vollert, Tobias Schuster. Ectopic Thymus. PedRad [serial online] vol 7, no. 7.
    URL: www.PedRad.info/?search=20070724201543


     

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    Ectopic Thymus
    Veronika Huf, Kurt Vollert, Tobias Schuster. Ectopic Thymus. PedRad [serial online] vol 7, no. 7.
    URL: www.PedRad.info/?search=20070724201543


     




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