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    Go to the top of the page   ID: 20040401105459 Original case in english  More links about this topic on Pubmed (PubMed Reader)
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    Reversible Ceftriaxone Associated Biliary Pseudolithiasis
    Dirk Schaper, IM Szargan. Reversible Ceftriaxone Associated Biliary Pseudolithiasis. PedRad [serial online] vol 4, no. 4.
    URL: www.PedRad.info/?search=20040401105459


     
     Pediatric Radiology CasesImages to this case: There are Ultrasound-images available for this case. [ Ultrasound ] View all modalities [ All ]   
     Pediatric Radiology CasesAuthor/s:

    Dirk Schaper, I.M. Szargan (St.Barbara-Krankenhaus Halle Kinderchirurgie)  

     
     Pediatric Radiology CasesEmail Address:

    Viewable for logged on visitors (Log on)  

     
     Pediatric Radiology CasesAge:

    14 Years  

     
     Pediatric Radiology CasesGender:

    Female  

     
     Pediatric Radiology CasesRegion-Organ:

    Abdomen-Other and unknown  

     
     Pediatric Radiology CasesMost likely etiology:

    other  

     
     Pediatric Radiology CasesHistory:

    14 year old girl with acute abdominal distress. Clinically, chemically and sonographically developed inflammatory process in the lower abdomen. Sonographic representation of the massively infectious appendix.

    Intraoperatively, diffuse peritonitis with perforated appendicitis. Antibiotic treatment with Ceftriaxone, as well as others. In the sonographic follow-ups, representation of the noticeable pathology.  

     
     Pediatric Radiology CasesPathomorphology or Pathophysiology of this disease :

    N/A  

     
     Pediatric Radiology CasesRadiological findings:


    -

    Ultrasound 1 <- view Ultrasound 1

    Ultrasound 1: Upper abdomen (longitudinal) in the medial clavicular line: Gall bladder not well-filled, multiple, low-echo, detrital-like concrements.

     

     
     Pediatric Radiology CasesDiagnosis confirmation:

    Imaging including endoscopy  

     
     Pediatric Radiology CasesWhich DD would be also possible with the radiological findings:

    Gallstones, sluge of other genesis.  

     
     Pediatric Radiology CasesCourse / Prognosis / Frequency / Other :

    In the follow-up examination 14 days after the last dose of ceftriaxone, the pseudolithiasis was gone. The patient felt fine, in regards to the gall bladder.  

     
     Pediatric Radiology CasesComments of the author about the case:

    The prevalence of gall stones in childhood is low. Increasingly more often, gall bladder sludge development is seen sonographically. Either through totally parenteral nutrition or short-bowel syndrome, precipitations of this type are usually only temporarily proven. In selected cases, however, they can be the origin of stone formation.

    In the case of an antibiotic treatment with ceftriaxone, it is recommended to look for such precipitations and to document their course. A surgical indication is usually not given. In our experience, sludge formation when using ceftriaxone is usually temporary. Even by giving this medication intravenously (short-infusion), we have seen this phenonemon. We have not seen a nephrolithiasis as described by de Moor et al..  

     
     Pediatric Radiology CasesFirst description / History:

    Schaad UB, Tschaeppeler H, Lentze MJ
    Transient formation of precipitations in the gallbladder associated with Ceftriaxon therapy.
    Pediatr Infect Dis J 1986; 5:708  

     
     Pediatric Radiology CasesLiterature:

    1. Medline: Medline
    Palanduz A, Yalcin I, Tonguc E, Guler N, Ones U, Salman N, Somer A
    Sonographic assessment of ceftriaxone-associated biliary pseudolithiasis in children.
    J Clin Ultrasound. 2000 May;28(4):166-8

    2. Medline: Medline
    Schaad UB, Wedgwood-Krucko J, Tschaeppeler H
    Reversible Ceftriaxon-associated biliary pseudolithiasis in children.
    Lancet II. 1988 :1411-1413

    3. Medline: Medline
    de Moor RA, Egberts AC, Schroder CH
    Ceftriaxone-associated nephrolithiasis and biliary pseudolithiasis.
    Eur J Pediatr. 1999 Dec;158(12):975-7.  

     
     Pediatric Radiology CasesKeywords:

    Gall bladder concrement, gall bladder sludge, reversible, Ceftriaxone associated, biliary pseudolithiasis, cholelithiasis, cholecystolithiasis, child, childhood, pediatric radiology  

     
     Pediatric Radiology Cases Cite this article:

    Dirk Schaper, IM Szargan. Reversible Ceftriaxone Associated Biliary Pseudolithiasis. PedRad [serial online] vol 4, no. 4.
    URL: www.PedRad.info/?search=20040401105459  

     
     Pediatric Radiology Cases Read similar articles: with corresponding keywords
    in the same field: Abdomen-Other and unknown
    or in the region: Abdomen
    or in the tissue/organ: Other and unknown
    or with the etiology: other
     
     Pediatric Radiology CasesImages to this case: There are Ultrasound-images available for this case. [ Ultrasound ] View all modalities [ All ]   
     
    Reversible Ceftriaxone Associated Biliary Pseudolithiasis
    Dirk Schaper, IM Szargan. Reversible Ceftriaxone Associated Biliary Pseudolithiasis. PedRad [serial online] vol 4, no. 4.
    URL: www.PedRad.info/?search=20040401105459


     

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    Reversible Ceftriaxone Associated Biliary Pseudolithiasis
    Other cases by these authors:

    Search Dirk Schaper in Medline Dirk Schaper (43)   
    Search I.M. Szargan in Medline I.M. Szargan (1)   

    Reversible Ceftriaxone Associated Biliary Pseudolithiasis  
     
    Reversible Ceftriaxone Associated Biliary Pseudolithiasis
    Dirk Schaper, IM Szargan. Reversible Ceftriaxone Associated Biliary Pseudolithiasis. PedRad [serial online] vol 4, no. 4.
    URL: www.PedRad.info/?search=20040401105459


     

    Which diagnosis have other collegues guessed?


    • Gall stones
      Votes: 3 (37 %)


    • Gall bladder polyps
      Votes: 0 (0 %)


    • Sludge
      Votes: 5 (62 %)


    • Physiological slicing phenonemon
      Votes: 0 (0 %)



        Total answers: 8

     
    Reversible Ceftriaxone Associated Biliary Pseudolithiasis
    Dirk Schaper, IM Szargan. Reversible Ceftriaxone Associated Biliary Pseudolithiasis. PedRad [serial online] vol 4, no. 4.
    URL: www.PedRad.info/?search=20040401105459


     

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    Reversible Ceftriaxone Associated Biliary Pseudolithiasis
    Dirk Schaper, IM Szargan. Reversible Ceftriaxone Associated Biliary Pseudolithiasis. PedRad [serial online] vol 4, no. 4.
    URL: www.PedRad.info/?search=20040401105459


     




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