KINDERRADIOLOGIE ONLINE - view radiology images and radiology cases
Lesen Sie diese Seite auf Deutsch   Read this page in English
The Peer Reviewed Pediatric Radiology Platform on the Web
ISSN: 1942-955X :: Publisher: EduRad ::Editor-In-Chief: Roland Talanow, MD, PhD  
Browse Browse || Search Search || Online Book Systematically Online Book Systematically || Discussion Forum Discussion Forum || News News || Submit a Case Submit a Case || Rules Rules |
Most Interesting Cases Most Interesting Cases || "Most Diligent" Authors "Most Diligent" Authors || Case of the Day Case of the Day || Teaching files Teaching files || Links Links |
Newsletter Newsletter || Start Start || Survey Survey || Your Opinion Your Opinion || My Profile My Profile || CME-Credits CME-Credits |
    Pediatric Radiology News / Ads / Jobs Get the Pediatric Radiology News as RSS feed !
    Send us your news or ads for free
  • Age related changes in brain MR appearance in the course of neurocutaneous melanosis.... (Eur J Radiol)
  • Impact of Chest Radiography on Antibiotic Treatment for Children With Suspected Pneumonia.... (Pediatr Emerg Care)
  • An observational study using ultrasound to assess physiological changes following fluid bolus admini... (BMC Pediatr)
  • CME Kurs: Paediatric Body MRI

  • CME course: Paediatric Body MRI

  • Universitätsklinikum Jena sucht eine Ärztin/einen Arzt in Weiterbildung in Vollzeit

  • Kinderspital Zürich sucht Oberärztin / Oberarzt (100 %)

  • Kinderradiologische Oberärztin / Oberarzt gesucht

  • 2 Stellen in der Kinderradiologie - 1 Assistenzärztin/Assistenzarzt und 1 Oberärztin/Oberarzt in Voll- oder Teilzeit

  • Senior Paediatric Radiologist in Pediatric Radiology section needed

  • Facharzt als Oberärztin / Oberarzt in Sektion Kinderradiologie gesucht

  • Stellenangebot für Assistenzarzt (m/w) zur Facharztausbildung für RADIOLOGIE und/oder KINDERRADIOLOGIE

  • „Fellow“-Stelle zur Weiterbildung in Pädiatrischer Radiologie am Kinderspital Zürich

  • Fellow-Stelle Pädiatrische Neuroradiologie

  • FFF Kinderradiologie - Muskuloskelettale Radiologie im Kindesalter (Fit für den Facharzt)

  • Assistenzarzt für Kinderradiologe gesucht an Universitätsklinikum Schleswig-Holstein, Campus Kiel

  • Turnusarzt (m/w) in Ausbildung zum Facharzt (m/w) für Radiologie

  • Assistenzarzt (m/w) zur Weiterbildung im Schwerpunkt Kinderradiologie

  • Send us your news or ads for free

    Get the Pediatric Radiology News as RSS feed !


    Radiolopolis

    The dynamic Radiology community for education, research and practice


     

    Go to the top of the page   ID: 20021217091236 Original case in english  More links about this topic on Pubmed (PubMed Reader)
    Add this case to your RSS feeder: Subscribe to RSS feed Add to Yahoo Add to Google Add to AOL Add to Furl Subscribe to Feed Burner feed

    Bookmark and Share


    | The Authors | Discussion | Write a Comment to this Case |
    | Evaluate this Case | Recommend this Case to a Colleague | Survey Results |
    | Citation | Similar Cases | Similar Cases in the Internet | Images to this Case |
     
    Meningeal spread in Hodgkin's disease
    Carsten Bock. Meningeal spread in Hodgkin's disease. PedRad [serial online] vol 2, no. 12.
    URL: www.PedRad.info/?search=20021217091236


     
     Pediatric Radiology CasesImages to this case: There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     Pediatric Radiology CasesAuthor/s:

    Carsten Bock (Halle)  

     
     Pediatric Radiology CasesEmail Address:

    Viewable for logged on visitors (Log on)  

     
     Pediatric Radiology CasesAge:

    18 Years  

     
     Pediatric Radiology CasesGender:

    N/A  

     
     Pediatric Radiology CasesRegion-Organ:

    Head-Brain and brain nerves  

     
     Pediatric Radiology CasesMost likely etiology:

    unknown  

     
     Pediatric Radiology CasesHistory:

    18 year-old patient with a second reoccurance of Hodgkin's disease. In the course of restaging, an MR examination of the head was done. No neurological symptoms. Multifocal reoccurance (various lymph node regions, liver, spine = Stage IV).  

     
     Pediatric Radiology CasesPathomorphology or Pathophysiology of this disease :

    A malignant lymphoma with Sternberg-Reed Giant cells as a histological characteristic. In the early stages, this is a local lymph node illness, but in further stages it is a systemic illness. Epidemiology: Incidence 3/100,000. m:w - 3:2. Peak age: 30-60 years. Classification can be divided into 4 subtypes (nodular-sclerosing, mixed, lymphocyte rich, lymphocyte poor), where the nodular-sclerosing for is most common in younger patients.
    Etiology is unknown.
    Seeding is initially lymphogenic, but later it can be hematogenic or continuous. Staging occurs upon the clinical signs (Ann-Arbor). Stage IV corresponds to a disseminated form.  

     
     Pediatric Radiology CasesRadiological findings:


    MRI 1 <- view MRI 1

    MRI 1: T1-weighted coronal image after contrast and before treatment: Obvious widening (about 1 cm) and pathologic contrast enhancement of the meningeal structures located parietally on both sides. MR-morohologically, one cannot distinguish between a dural or a leptomeningeal affliction, however the smooth contours intracerebrally and the absence of contrast in the sulci point to a dural infiltration.







    MRI 2 <- view MRI 2

    MRI 2: T1-weighted image coronal after contrast: Following slice of Image 1.







    MRI 3 <- view MRI 3

    MRI 3: T1-weighted image coronal after contrast (slice position as in image 1) 12 days after chemotherapy. There is an obvious regression of the meningeal widening with unchanged contrast enhancement.







    MRI 4 <- view MRI 4

    MRI 4: T1-weighted image coronal after contrast. 12 days after chemotherapy. Neighboring slice as in Image 3, slice position as in the second image.




     

     
     Pediatric Radiology CasesDiagnosis confirmation:

    Expert's opinion  

     
     Pediatric Radiology CasesWhich DD would be also possible with the radiological findings:

    Meningeal metastases (i.e. neuroblastoma), inflammatory changes, meningeomas (more centrally located, near the middle, solid).  

     
     Pediatric Radiology CasesCourse / Prognosis / Frequency / Other :

    A brain infiltration in Hodgkin's disease is rare. Between 1954 and 1999 there have only been 48 cases reported. Stein and Lennert's autopsy statistics showed 5 percent of the patients with Hodgkin's disease had dural infiltration. The spreading to intracranial structures is suspected to be hematogenic.  

     
     Pediatric Radiology CasesComments of the author about the case:

    N/A  

     
     Pediatric Radiology CasesFirst description / History:

    N/A  

     
     Pediatric Radiology CasesLiterature:

    1. Medline: Medline
    Nakayama, H. et al.
    Brain Involvement in Hodgkin´s Disease: Case Report and Review of the Literature.
    Radiation Medicine: Vol. 18 No. 3, 205208 p.p., 2000.

    2. Medline: Medline
    Eder, M., P. Gedigk
    Lehrbuch der Allgemeinen Pathologie und der Pathologischen Anatomie
    Springer 1986, 32. Auflage S. 430-434.

    3. Medline: Medline
    AWMF online - Leitlinie Pädiatrische Onkologie/Hämatologie: M. Hodgkin.  

     
     Pediatric Radiology CasesKeywords:

    Hodgkin's disease, meningeal participation, meningeal spread, child, childhood, pediatric radiology  

     
     Pediatric Radiology Cases Cite this article:

    Carsten Bock. Meningeal spread in Hodgkin's disease. PedRad [serial online] vol 2, no. 12.
    URL: www.PedRad.info/?search=20021217091236  

     
     Pediatric Radiology Cases Read similar articles: with corresponding keywords
    in the same field: Head-Brain and brain nerves
    or in the region: Head
    or in the tissue/organ: Brain and brain nerves
    or with the etiology: unknown
     
     Pediatric Radiology CasesImages to this case: There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     
    Meningeal spread in Hodgkin's disease
    Carsten Bock. Meningeal spread in Hodgkin's disease. PedRad [serial online] vol 2, no. 12.
    URL: www.PedRad.info/?search=20021217091236


     

    Search similar cases in:
    More links about this topic on Pubmed  More links about this topic on Yahoo  More links about this topic on Altavista  More links about this topic on MSN  More links about this topic on Google  More links about this topic on Fireball

    Peer-reviewed Radiology Search



    Meningeal spread in Hodgkin's disease
    Other cases by these authors:

    Search Carsten Bock in Medline Carsten Bock (9)   

    Meningeal spread in Hodgkin's disease  
     
    Meningeal spread in Hodgkin's disease
    Carsten Bock. Meningeal spread in Hodgkin's disease. PedRad [serial online] vol 2, no. 12.
    URL: www.PedRad.info/?search=20021217091236


     

    Which diagnosis have other collegues guessed?


    • Meningeoma in Hodgkin's disease
      Votes: 1 (9 %)


    • Meningitis
      Votes: 1 (9 %)


    • Meningeal infiltration in Hodgkin's disease
      Votes: 8 (72 %)


    • Coincidence of Hodgkin's disease and Hyperostosis frontalis
      Votes: 1 (9 %)



        Total answers: 11

     
    Meningeal spread in Hodgkin's disease
    Carsten Bock. Meningeal spread in Hodgkin's disease. PedRad [serial online] vol 2, no. 12.
    URL: www.PedRad.info/?search=20021217091236


     

    Medical Dictionary
    Search in medical dictionary for
    Or type in a keyword
    ( Provided by The On-Line Medical Dictionary )




    How interesting was this case for you?
    (10 = most interesting || 1 = less interesting)
     
    Meningeal spread in Hodgkin's disease
    Carsten Bock. Meningeal spread in Hodgkin's disease. PedRad [serial online] vol 2, no. 12.
    URL: www.PedRad.info/?search=20021217091236


     




    Discussion >> Write Comment <<



      There are no comments available regarding this case.





     Write a comment to this case (With * marked fields have to be filled)

    Type in this number: 6844

    Name: *

    E-Mail:

    Website:

    Subject: *

    Text: *




     
      Pediatric Radiology Discussion Get the Pediatric Radiology Discussion as RSS feed !
      To the discussion forum
      To the discussion forum

      Get the Pediatric Radiology Discussion as RSS feed !

      © 2001-2016   www.kinderradiologie-online.de
      In cooperation with © Radiolopolis - Radiology Search - Radiology Teacher - PubMed Reader - Annotate - Radiology Lectures & Tutorials - Radiology Boards Preparation - Pediatric Radiology Links - Pediatric Radiology Information - Emergency Radiology - Lung Cancers - USMLE Forums - Cancer Staging Information - Chest Radiology - Radiology Case Report Journal
      For suggestions and questions: information@kinderradiologie-online.de
      Add this site to your favorites (CTRL+D)