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    Go to the top of the page   ID: 20011128193914 Original case in english  More links about this topic on Pubmed (PubMed Reader)
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    Fibrolamellar liver carcinoma in the childhood
    A Schlüter. Fibrolamellar liver carcinoma in the childhood. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011128193914


    ( There are questions in the CMK-Mode for this topic )

     
     Pediatric Radiology CasesImages to this case: There are CT-images available for this case. [ CT ] There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     Pediatric Radiology CasesAuthor/s:

    A. Schlüter (Halle)  

     
     Pediatric Radiology CasesEmail Address:

    Viewable for logged on visitors (Log on)  

     
     Pediatric Radiology CasesAge:

    14 Years  

     
     Pediatric Radiology CasesGender:

    Female  

     
     Pediatric Radiology CasesRegion-Organ:

    Abdomen-Liver  

     
     Pediatric Radiology CasesMost likely etiology:

    neoplastic  

     
     Pediatric Radiology CasesHistory:

    14 year-old female patient with a palpable tumor in the right hypochondrium at the point of diagnosis. Pain on pressure, icterus.  

     
     Pediatric Radiology CasesPathomorphology or Pathophysiology of this disease :

    This rare disease is observed predominantly in the 2nd and 3rd decade of life. In contrast to the hepatocellular carcinoma, no etiological connection to cirrhosis of the liver exists. Frequently, most solitary tumors already have a diameter of more than 10 cm in the initial diagnosis of the disease. Regressive variations are are frequent; in 30%, calcifications possible. Intrahepatic metastases as well as other organ metastases are are possible.  

     
     Pediatric Radiology CasesRadiological findings:


    CT 1 <- view CT 1

    CT 1: Spoke-wheel characteristic of the tumor (particularly after contrast application). Proof of central calcifications, as well as regressive tumor parenchymal changes. Inhomogenic contrast uptake in the right hepatic lobe when portal vessels are compressed.







    MRI 1 <- view MRI 1

    MRI 1: MRCP: Ectasias in the intrahepatic biliary duct because of tumor compression in the portal portion of the DHC.







    MRI 2 <- view MRI 2

    MRI 2: T2-coronal, Spoke-wheel characteristic of the tumor (particularly after contrast application). Proof of central calcifications, as well as regressive tumor parenchymal changes.







    MRI 3 <- view MRI 3

    MRI 3: T1-SE transversal, Spoke-wheel characteristic of the tumor (particularly after contrast application). Proof of central calcifications, as well as regressive tumor parenchymal changes. Inhomogenic contrast uptake in the right hepatic lobe when portal vessels are compressed.




     

     
     Pediatric Radiology CasesDiagnosis confirmation:

    Surgery / Histo  

     
     Pediatric Radiology CasesWhich DD would be also possible with the radiological findings:

    The whole constellation - particularly the proof of calcifications as well as the wheel-spoke character of the lesions - are typical for the fibrolamellar liver carcinoma. Differentials which should be considered are benign tumors (FNH, Adenoma).  

     
     Pediatric Radiology CasesCourse / Prognosis / Frequency / Other :

    The illness is rare. The diagnosis is often made in late stages of the illness. Mostly a solitary finding. Metastases are possible. The prognosis is principally not good. It is dependent on: if the tumor is able to be resected and if metastases are found. Reoccurrances have been described after surgical intervention. Local or systemic chemotherapy increase the tumor-free intervals.  

     
     Pediatric Radiology CasesComments of the author about the case:

    N/A  

     
     Pediatric Radiology CasesFirst description / History:

    N/A  

     
     Pediatric Radiology CasesLiterature:

    1. Medline: Medline
    Ichikawa T, Federle M P, Grazioli L, Marsh W.
    Fibrolamellar hepatocellular carcinoma: pre- and posttherapy evaluation with CT and MR imaging.
    Radiology 2000; 217, 145-151  

     
     Pediatric Radiology CasesKeywords:

    Fibrolamellaric liver carcinoma, liver tumor, Fibrolamellar liver carcinoma, abdominal tumor, pain, icterus, child, childhood, pediatric radiology  

     
     Pediatric Radiology Cases Cite this article:

    A Schlüter. Fibrolamellar liver carcinoma in the childhood. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011128193914  

     
     Pediatric Radiology Cases Read similar articles: with corresponding keywords
    in the same field: Abdomen-Liver
    or in the region: Abdomen
    or in the tissue/organ: Liver
    or with the etiology: neoplastic
     
     Pediatric Radiology CasesImages to this case: There are CT-images available for this case. [ CT ] There are MRI-images available for this case. [ MRI ] View all modalities [ All ]   
     
    Fibrolamellar liver carcinoma in the childhood
    A Schlüter. Fibrolamellar liver carcinoma in the childhood. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011128193914


    ( There are questions in the CMK-Mode for this topic )

     

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    Fibrolamellar liver carcinoma in the childhood
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    Search A. Schlüter in Medline A. Schlüter (7)   

    Fibrolamellar liver carcinoma in the childhood  
     
    Fibrolamellar liver carcinoma in the childhood
    A Schlüter. Fibrolamellar liver carcinoma in the childhood. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011128193914


    ( There are questions in the CMK-Mode for this topic )

     
     
    Fibrolamellar liver carcinoma in the childhood
    A Schlüter. Fibrolamellar liver carcinoma in the childhood. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011128193914


    ( There are questions in the CMK-Mode for this topic )

     

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    Fibrolamellar liver carcinoma in the childhood
    A Schlüter. Fibrolamellar liver carcinoma in the childhood. PedRad [serial online] vol 1, no. 11.
    URL: www.PedRad.info/?search=20011128193914


    ( There are questions in the CMK-Mode for this topic )

     




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